Damus–Kaye–Stansel Procedure #3: Double-Barrel DKS Anastomosis
1. Concept
The double-barrel Damus–Kaye–Stansel (DKS) anastomosis is a surgical strategy designed to relieve or prevent systemic ventricular outflow tract obstruction (SVOTO) in patients with functionally single-ventricle physiology, particularly when the native aortic outflow is restrictive, malaligned, or vulnerable to progressive obstruction during staged palliation.
Rather than simply bypassing a narrowed subaortic pathway, the double-barrel DKS reconstructs the aortic root and pulmonary root as a bivalved common systemic outlet. By incorporating the pulmonary root into the systemic outflow pathway, the operation creates a wide, low-resistance channel from the systemic ventricle to the ascending aorta [1, 2].
2. Surgical Principle
The essential concept of the double-barrel technique is geometric preservation.
Both great arteries are transected above the semilunar valves, and the adjacent aortic and pulmonary roots are anastomosed laterally. The reconstructed root complex is then connected to the ascending aorta. If the ascending aorta is small or there is a size discrepancy between the reconstructed proximal outflow and the distal aorta, patch augmentation may be added to create a nonrestrictive anastomosis.
The operation can be summarized in four steps:
- Transection of the ascending aorta and main pulmonary artery
- Creation of a side-by-side root complex
- Reconstruction of the systemic outflow pathway
- Preservation of semilunar valve geometry
Both great arteries are divided above the semilunar valves.
The aortic and pulmonary roots are approximated and anastomosed laterally, producing the characteristic “double-barrel” configuration.
The augmented common root is connected to the ascending aorta, with patch enlargement when needed.
The pulmonary root becomes part of the systemic outflow pathway; therefore, avoiding sinus distortion is critical for long-term valve competence [1].
3. Hemodynamic Rationale
In single-ventricle physiology, SVOTO is particularly harmful because the systemic ventricle must support the entire systemic circulation through a limited outflow pathway. Progressive obstruction increases ventricular afterload, promotes hypertrophy, raises end-diastolic pressure, and may impair candidacy for subsequent Glenn and Fontan completion.
The DKS operation addresses this problem by redirecting systemic ventricular output through the pulmonary root, which is often larger and less obstructed than the native aortic outlet. When performed before significant ventricular dysfunction or progressive subaortic narrowing develops, the procedure can stabilize the systemic pathway and protect long-term ventricular performance [3, 4].
4. Why the Double-Barrel Technique Matters
The major technical advantage of the double-barrel DKS is that it creates a wide and symmetric systemic outflow tract while preserving the shape of the pulmonary sinus. This is clinically important because the pulmonary valve becomes exposed to systemic pressure after reconstruction.
Comparative data suggest that the double-barrel technique may better preserve pulmonary valve function than end-to-side DKS. In a series comparing double-barrel and end-to-side reconstructions, deterioration of pulmonary regurgitation was significantly less frequent after double-barrel DKS, and no patient required surgical reintervention for recurrent systemic outflow obstruction during follow-up [1].
This finding supports an important surgical principle:
the success of DKS is not determined only by the size of the anastomosis, but also by preservation of root geometry.
5. Clinical Outcomes
Published series generally support DKS as an effective method for managing SVOTO in single-ventricle pathways. Double-barrel DKS has been associated with durable relief of obstruction, low recurrence of SVOTO, and acceptable midterm to long-term survival [2, 3, 5].
In patients undergoing DKS at the time of cavopulmonary connection, survival and outflow durability have been favorable, with low rates of recurrent gradient and generally preserved neoaortic valve function [3]. Prophylactic DKS performed concomitantly with bidirectional Glenn has also been reported as a strategy to prevent late SVOTO in anatomically high-risk patients before Fontan completion [4].
However, semilunar valve competence remains a key long-term concern. Earlier experience with DKS demonstrated that pulmonary valve incompetence can occur after reconstruction, emphasizing the need to minimize pulmonary sinus distortion and to select the appropriate operative configuration for each patient [6, 7].
6. Technical Considerations
The double-barrel DKS is fundamentally a procedure of three-dimensional alignment. A technically successful reconstruction should achieve:
- A wide and nonrestrictive systemic outlet
- Minimal tension between the reconstructed root and ascending aorta
- No torsion or kinking of the great arterial roots
- Preservation of pulmonary sinus geometry
- Avoidance of pulmonary valve distortion
- No compression or distortion of the branch pulmonary arteries
Patch augmentation should be considered when the ascending aorta is small, the proximal root complex is larger than the distal aorta, or the anastomosis appears at risk for narrowing. Several technical modifications have been described to avoid prosthetic material, reduce root distortion, and improve the geometry of the reconstructed outflow tract [8, 9].
7. Practical Surgical Perspective
From the surgeon’s viewpoint, the double-barrel DKS should be understood as a root-reconstruction operation, not merely an outflow bypass.
The objective is to transform two adjacent semilunar roots into a single, durable, bivalved systemic channel. The pulmonary root must be treated as a future systemic root, and therefore its sinus geometry and valve competence are central to the long-term result.
The optimal reconstruction is:
- broad enough to prevent recurrent SVOTO;
- symmetric enough to avoid abnormal flow acceleration;
- gentle enough to preserve semilunar valve function;
- durable enough to support subsequent staged palliation.
8. Summary
The double-barrel DKS anastomosis transects both great arteries and reconstructs the aortic and pulmonary roots into a bivalved common systemic outflow tract. Its primary goal is durable relief or prevention of SVOTO in single-ventricle physiology.
Compared with more asymmetric end-to-side variants, the double-barrel technique offers a more balanced reconstruction and may better preserve pulmonary valve function by minimizing pulmonary sinus distortion. The central surgical principle is geometry: a wide, tension-free, symmetric, and valve-preserving neo-systemic outflow pathway is the foundation of a durable DKS repair.
References
[1] Fujii Y, Kasahara S, Kotani Y, Takagaki M, Arai S, Otsuki S, Sano S. Double-barrel Damus-Kaye-Stansel operation is better than end-to-side Damus-Kaye-Stansel operation for preserving the pulmonary valve function: the importance of preserving the shape of the pulmonary sinus. J Thorac Cardiovasc Surg. 2011;141(1):193-199.
[2] Fiore AC, Rodefeld M, Vijay P, Turrentine M, Seithel C, Ruzmetov M, Brown JW. Subaortic obstruction in univentricular heart: results using the double barrel Damus-Kaye Stansel operation. Eur J Cardiothorac Surg. 2009;35(1):141-146.
[3] Alsoufi B, Al-Wadai A, Khan M, Al-Ahmadi M, Kalloghlian A, Bulbul Z, Al-Fayyadh M, Al-Halees Z. Outcomes of Damus-Kaye-Stansel anastomosis at time of cavopulmonary connection in single ventricle patients at risk of developing systemic ventricular outflow tract obstruction. Eur J Cardiothorac Surg. 2014;45(1):77-82.
[4] Shimada M, Hoashi T, Kagisaki K, Shiraishi I, Yagihara T, Ichikawa H. Clinical outcomes of prophylactic Damus-Kaye-Stansel anastomosis concomitant with bidirectional Glenn procedure. J Thorac Cardiovasc Surg. 2012;143(1):137-143.e1.
[5] Yang CK, Jang WS, Choi ES, Cho S, Choi K, Nam J, Kim WH. The clinical outcomes of Damus-Kaye-Stansel procedure according to surgical technique. Korean J Thorac Cardiovasc Surg. 2014;47(4):344-349.
[6] McElhinney DB, Reddy VM, Silverman NH, Hanley FL. Modified Damus-Kaye-Stansel procedure for single ventricle, subaortic stenosis, and arch obstruction in neonates and infants: midterm results and techniques for avoiding circulatory arrest. J Thorac Cardiovasc Surg. 1997;114(5):718-726.
[7] Lui RC, Williams WG, Trusler GA, Freedom RM, Coles JG, Rebeyka IM, Smallhorn J. Experience with the Damus-Kaye-Stansel procedure for children with Taussig-Bing hearts or univentricular hearts with subaortic stenosis. Circulation. 1993;88(5 Pt 2):II170-II176.
[8] Park CS, Lee CH, Kwak JG, Lee C. Modification of the Damus-Kaye-Stansel procedure. Ann Thorac Surg. 2010;90(1):315-316.
[9] Rosenblum J, Anvari F, Alsoufi B. The Damus-Kaye-Stansel operation: management of systemic ventricular outflow tract obstruction. Multimed Man Cardiothorac Surg. 2018;2018:mmx017.
[10] Al-Akhfash AA, Kabbani MS, Abu-Sulaiman RM, Tamimi OR, Elbarbary MA, Najm HK. Outcome of Norwood and Damus-Kaye-Stansel procedures for univentricular congenital heart anomalies. Saudi Med J. 2009;30(3):340-345.